Local plumber John Price, was told in 2001 there was no more that could be done for him; his kidney cancer had spread to his leg, lungs and stomach.
"I'd prepared myself for the worst but was asked if I would help test a new drug on a clinical trail at the Weston Park Hospital Cancer Research Centre. There was nothing to lose and, as it happened, a whole life to be gained. The drug not only stopped the tumours growing, it also shrank them and it's why I am still here today.
"I still attend clinic in the Cancer Research Centre and meet with other kidney cancer patients. Treatments have moved on since then and I know that if I ever need it again I will get the latest, most effective treatment possible.
"People need to realise how lucky we are having this world class Cancer Research Centre here in South Yorkshire. The knowledge and expertise is second to none. Whether you are from Doncaster, Dronfield or Darnall, cutting-edge cancer research and the latest treatments and drugs are available to you.
"This research has given me precious, extra, quality years with my family - longer than I could ever have dreamed. I've set a goal of seeing my sons graduate. If I get there I will set another goal.
"In the meantime I urge you to make a donation - if for no other reason than it is inevitable that cancer will affect you or someone in your close family or perhaps a very good friend.
"It is research that is driving treatment forward and giving us more, better quality time.
"A donation is a small price to pay."
For patient Sue Higgins, from Sheffield, being involved in a clinical trial meant fewer radiotherapy treatment sessions, fewer side effects, less disruption and an equally effective treatment.
" I had a lump on my cheek which was diagnosed as Lymphoma in my salivary gland. I was told I would need 12 sessions of radiotherapy but was given the opportunity to take part in a clinical trial testing the effects of just 2 sessions. I was worried but reassured that if 2 didn't work I could have more so I decided to give it a go.
"I'm glad I did. It certainly was 'an opportunity'. I know it will help others in the future and the benefits for me were immediate. I only had to come to hospital over two days. the lump started to shrink at once an within two weeks you couldn't see it at all. I was so pleased. Even with 2 treatments I had a sticky mouth - 12 would have damaged my salivary gland leaving me with a dry mouth for ever after and I would have needed weeks to recuperate.
"It's been nearly a year now and all seems well - touch wood. I only had one uncomfortable week which is nothing compared to what some have to put up with. I am very grateful and am still seen every 3 months so I know I am very well looked after.
A gift to cancer research at Weston Park Hospital is a gift for the future.It has very real benefits here and now for people like me. I might not have had this opportunity without the Weston Park Hospital Cancer Appeal. Things are getting better all the time. Please do what you can to help."
